Thursday, January 31, 2013

Various political speakers highlight Catholic Schools Week in Rome

Story Created: Jan 29, 2013 at 4:28 PM EST

Story Updated: Jan 29, 2013 at 5:21 PM EST

ROME, N.Y. (WKTV) - In recognition of Catholic Schools Week, Rome Catholic School has invited various politicians into the classrooms to see the work that is being done.

Rome Mayor Joe Fusco spoke to grades seven through 12 on Tuesday about government and getting involved. He says there was one point he wanted the students to remember.

"They can be part of the process," Mayor Fusco said. "It's not this thing that exists downtown or in Albany or in Washington. It's your community. All politics are local."

Rome Catholic School will continue to observe National Catholic Schools Week through Friday, with different speakers scheduled for each day.

Source: http://www.wktv.com/news/local/Various-political-speakers-highlight-Catholic-Schools-Week-in-Rome-188900611.html

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Wednesday, January 30, 2013

US military deaths in Afghanistan at 2,045

As of Tuesday, Jan. 29, 2013, at least 2,045 members of the U.S. military had died in Afghanistan as a result of the U.S.-led invasion of Afghanistan in late 2001, according to an Associated Press count.

The AP count is two less than the Defense Department's tally, last updated Tuesday at 10 a.m. EST.

At least 1,706 military service members have died in Afghanistan as a result of hostile action, according to the military's numbers.

Outside of Afghanistan, the department reports at least 118 more members of the U.S. military died in support of Operation Enduring Freedom. Of those, 11 were the result of hostile action.

The AP count of total OEF casualties outside of Afghanistan is five more than the department's tally.

The Defense Department also counts three military civilian deaths.

Since the start of U.S. military operations in Afghanistan, 18,215 U.S. service members have been wounded in hostile action, according to the Defense Department.

___

The latest identifications reported by the military:

?Sgt. Mark H. Schoonhoven, 38, of Plainwell, Mich., died Jan. 20 at Brooke Army Medical Center, Fort Sam Houston, Texas from wounds suffered when enemy forces attacked his unit with an improvised explosive device on Dec. 15, 2012 in Kabul, Afghanistan; assigned to the 32nd Transportation Company, 43rd Sustainment Brigade, 4th Infantry Division, Fort Carson, Colo.

___

Online:

http://www.defense.gov/news/

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-29-Afghan-US%20Deaths/id-8421aa487d364909b77710b0b1cc3ac3

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Apartment Careers: jobs, Austin jobs, Texas jobs, Assistant Business ...

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Pinnacle has ongoing employment opportunities at our headquarters in Seattle, our more than 40 branch office locations nationally and our many managed communities throughout the country.

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  • Assist in managing the propertys budget by making sound fiscal decisions to increase the net operating income of the community.
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    Source: http://hershel33.typepad.com/blog/2013/01/apartment-careers-jobs-austin-jobs-texas-jobs-assistant-business.html

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    Roma artist, writer on Nazi atrocities, dies at 79

    VIENNA (AP) ? Ceija Stojka survived three Nazi death camps and then found her life's work: Raising awareness of the Nazis' persecution of Roma ? also known as Gypsies ? in her art and her writings.

    Stojka carried the horrors of those camps with her until she was in her 50s, speaking out in words and pictures only decades after she was liberated from the Bergen-Belsen camp at age 12.

    Her death Monday at age 79 in a Vienna hospital was announced by her publisher. The Budapest-based European Roma Cultural Foundation described Stokja's concentration-camp themed paintings to The Associated Press on Wednesday as reflecting "entrenched sorrow in the bodies and spirit of the victims."

    Austrian Education and Culture Minister Claudia Schmied lauded Stojka's work in exposing Roma suffering under the Nazis, saying her advocacy gave rise to "hope that the oath 'Never Again!' is and will remain more than a historic promise."

    Her family's persecution under the Nazis began in 1941 and ended four years later with Stojka's liberation from the Bergen-Belsen camp in Germany. While her mother and four siblings also survived, Stojka's father and brother were killed in Auschwitz, two of the more than 1 million Roma estimated to have been killed under Hitler. In all, nearly 200 members of her extended family perished under the Nazis.

    Stojka kept those experiences to herself for decades at a time most Austrians embraced the popular notion that they and their nation were victims of Hitler instead of his willing accomplices.

    "If I could write down all my thoughts, they would surely be an endless book of suffering," she told an interviewer before embarking on her 1988 autobiography "We Live in Seclusion." ''But my thoughts race more quickly than my hands are able to put everything to paper."

    Born in Austria to a nomadic family of horse traders, Stojka returned after the end of the Nazi era and made a living selling carpets. She started speaking out in the 1980s, as Austrian awareness of the country's complicity in Nazi crimes grew. And she started painting ? dark somber pictures depicting the death camps that alternated with joyful images of pre-war life on the road in her family's horse-drawn wagon.

    Despite those happier images, she never forgot the horrors of the Nazi era ? and implored audiences not to let history repeat itself.

    "How is it possible at the beginning of the new century that the Roma population ... is still humiliated and maltreated ? and sometimes killed as it happened in Hungary ? for the only reason of being Roma?" she asked a gathering of Hungarian university and high-school students three years ago after a spate of Roma hate killings there.

    "Let my grandchildren live," she declared.

    Source: http://news.yahoo.com/roma-artist-writer-nazi-atrocities-dies-79-114818877.html

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    Tuesday, January 29, 2013

    Oil jumps on home price data; gasoline up to $3.36

    NEW YORK (AP) ? The price of oil climbed above $97 a barrel as home prices in the U.S. accelerated and stock markets resumed their rise toward record levels.

    Benchmark oil for March delivery rose $1, or 1 percent, to $97.44 a barrel around midday on the New York Mercantile Exchange. Oil hasn't closed above $97 in New York since Sept. 14.

    Oil is now up more than $5 a barrel this year and U.S. drivers may have noticed gas prices creeping higher. The average price for a gallon of gas Tuesday was $3.36, up 5 cents in the past week.

    Signs of improvement in the global economy are driving the increase in oil prices.

    A report Tuesday showed U.S. home prices in November had the biggest year-over-year increase in six years. That added to evidence showing that the U.S. housing market is recovering and outweighed a separate report indicating that higher taxes and an uncertain economic picture are sapping consumers' confidence.

    Those were the latest reports in a big week for U.S. economic indicators. The government will also this week release the latest numbers on weekly jobless claims, January unemployment and fourth-quarter growth. And the Federal Reserve's policy committee is holding a two-day meeting that concludes on Wednesday.

    U.S. stocks are approaching record levels after a January rally that has pushed the Dow Jones industrial average 6.2 percent higher this month. And the Standard & Poor's 500 index is up 5.3 percent, its highest level since December 2007.

    Brent crude, used to price international varieties of oil, rose 57 cents to $114.05 a barrel on the ICE Futures exchange in London.

    In other energy futures trading on Nymex:

    ? Wholesale gasoline rose 2 cents to $2.96 per gallon.

    ? Natural gas lost 6 cents to $3.25 per 1,000 cubic feet.

    ? Heating oil gained 3 cents to $3.09 a gallon.

    ___

    Pamela Sampson in Bangkok and Pablo Gorondi in Budapest contributed to this report.

    Source: http://news.yahoo.com/oil-jumps-home-price-data-gasoline-3-36-174634733--finance.html

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    The Montreal Heart Institute designated as a North American Center of Excellence

    The Montreal Heart Institute designated as a North American Center of Excellence [ Back to EurekAlert! ] Public release date: 28-Jan-2013
    [ | E-mail | Share Share ]

    Contact: Marie-Jose Nantel
    marie-josee.nantel@icm-mhi.org
    514-376-3330
    Montreal Heart Institute

    Percutaneous treatment of mitral valve failure

    Montral, January 28, 2013 The Montreal Heart Institute has just been designated as a Center of Excellence by Abbott Vascular for the percutaneous treatment of mitral valve failure with their MitraClip system. The MHI has therefore become a reference centre for this procedure for all hospitals across Canada and many other hospitals in North America.

    "The Montreal Heart Institute is delighted to receive this honour and international recognition. This designation, which we received for the quality of our care and our effective, cutting-edge program, will allow us to share our expertise with the international medical community and significantly contribute to improving care for patients with mitral valve and heart failure," said Dr. Philippe L. L'Allier, director of interventional cardiology at the MHI.

    The MHI joins Cedars-Sinai in Los Angeles (California) and the University of Virginia Health System (Virginia) to form a three-partner team that will train other medical centres in North America looking to start a clinical program for the percutaneous treatment of mitral valve failure with the MitraClip system.

    Thanks to the exceptional clinical work of a multidisciplinary team, made up of Dr. Anita Asgar and Dr. Raoul Bonan from the Department of Interventional Cardiology, Dr. Anique Ducharme and Dr. Arsne Basmadjian from the Department of Echocardiography, and Dr. Jennifer Cogan and Dr. Alain Deschamps from the Department of Anesthesiology, the MHI is considered as a model to emulate.

    Percutaneous implantation of the MitraClip system: an effective therapy

    For some patients, the implantation of the MitraClip system is a preferable alternative to heart surgery. Until now, mitral valve failure has been treated with medication or open-heart surgery depending on the degree of severity and the primary cause. This system is a minimally invasive option for mitral regurgitation, as the interventional cardiologist makes a 3-mm incision in the groin and uses catheters to position the clip in the mitral valve without having to stop the heart. Currently, the typical population for this treatment includes inoperable or high-risk surgical patients, as the procedure poses fewer risks of complications compared to conventional surgery. Patients are generally discharged from hospital within 48 hours of surgery and do not have to undergo difficult rehabilitation.

    "By allowing patients to regain independence and quality of life, this treatment reduces the number of hospital admissions and visits to emergency due to symptom reoccurrence," explained Dr. Asgar.

    About mitral valve failure

    Mitral valve failure (or mitral valve regurgitation) is the most common type of heart valve disease. This condition occurs when the anterior and posterior flaps of the valve do not close completely, which causes abnormal blood backflow from the left ventricle to the left atrium. The bigger the leak, the more blood the left ventricle has to pump to maintain adequate cardiac output. In the long term, mitral valve failure can lead to many complications, such as left ventricle dilation, atrial fibrillation and heart failure.

    ###

    About the Montreal Heart Institute: www.icm-mhi.org

    Information:

    Marie-Jose Nantel
    Communications Officer
    Montreal Heart Institute
    Phone: 514-376-3330, extension 2641 | marie-josee.nantel@icm-mhi.org



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    The Montreal Heart Institute designated as a North American Center of Excellence [ Back to EurekAlert! ] Public release date: 28-Jan-2013
    [ | E-mail | Share Share ]

    Contact: Marie-Jose Nantel
    marie-josee.nantel@icm-mhi.org
    514-376-3330
    Montreal Heart Institute

    Percutaneous treatment of mitral valve failure

    Montral, January 28, 2013 The Montreal Heart Institute has just been designated as a Center of Excellence by Abbott Vascular for the percutaneous treatment of mitral valve failure with their MitraClip system. The MHI has therefore become a reference centre for this procedure for all hospitals across Canada and many other hospitals in North America.

    "The Montreal Heart Institute is delighted to receive this honour and international recognition. This designation, which we received for the quality of our care and our effective, cutting-edge program, will allow us to share our expertise with the international medical community and significantly contribute to improving care for patients with mitral valve and heart failure," said Dr. Philippe L. L'Allier, director of interventional cardiology at the MHI.

    The MHI joins Cedars-Sinai in Los Angeles (California) and the University of Virginia Health System (Virginia) to form a three-partner team that will train other medical centres in North America looking to start a clinical program for the percutaneous treatment of mitral valve failure with the MitraClip system.

    Thanks to the exceptional clinical work of a multidisciplinary team, made up of Dr. Anita Asgar and Dr. Raoul Bonan from the Department of Interventional Cardiology, Dr. Anique Ducharme and Dr. Arsne Basmadjian from the Department of Echocardiography, and Dr. Jennifer Cogan and Dr. Alain Deschamps from the Department of Anesthesiology, the MHI is considered as a model to emulate.

    Percutaneous implantation of the MitraClip system: an effective therapy

    For some patients, the implantation of the MitraClip system is a preferable alternative to heart surgery. Until now, mitral valve failure has been treated with medication or open-heart surgery depending on the degree of severity and the primary cause. This system is a minimally invasive option for mitral regurgitation, as the interventional cardiologist makes a 3-mm incision in the groin and uses catheters to position the clip in the mitral valve without having to stop the heart. Currently, the typical population for this treatment includes inoperable or high-risk surgical patients, as the procedure poses fewer risks of complications compared to conventional surgery. Patients are generally discharged from hospital within 48 hours of surgery and do not have to undergo difficult rehabilitation.

    "By allowing patients to regain independence and quality of life, this treatment reduces the number of hospital admissions and visits to emergency due to symptom reoccurrence," explained Dr. Asgar.

    About mitral valve failure

    Mitral valve failure (or mitral valve regurgitation) is the most common type of heart valve disease. This condition occurs when the anterior and posterior flaps of the valve do not close completely, which causes abnormal blood backflow from the left ventricle to the left atrium. The bigger the leak, the more blood the left ventricle has to pump to maintain adequate cardiac output. In the long term, mitral valve failure can lead to many complications, such as left ventricle dilation, atrial fibrillation and heart failure.

    ###

    About the Montreal Heart Institute: www.icm-mhi.org

    Information:

    Marie-Jose Nantel
    Communications Officer
    Montreal Heart Institute
    Phone: 514-376-3330, extension 2641 | marie-josee.nantel@icm-mhi.org



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    Source: http://www.eurekalert.org/pub_releases/2013-01/mhi-tmh012813.php

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    Today in History

    Please check the URL for proper spelling and capitalization. If you're having trouble locating a destination on Yahoo!, try visiting the Yahoo! homepage or look through a list of Yahoo!'s online services.

    Please try Yahoo Help Central if you need more assistance.

    Source: http://news.yahoo.com/today-history-050206767.html

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    Monday, January 28, 2013

    Microbes Survive, and Maybe Thrive, High In the Atmosphere

    ...to find life in places that they hadn't previously considered that they'd find it.

    Yet, on the other hand, a lot of science fiction has covered such topics. Even HG Wells' War of the Worlds concludes with the deaths of the Martians, all of them , because of bacterial contamination and the lack of immunity. For all to have died, simply getting into contact with flora and fauna wouldn't be enough, it'd have to be airborne.

    Amusingly enough, there's probably life on Mars right now. If it wasn't ther

    Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/65U7kaneejk/story01.htm

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    What?s next for Anthony Pettis? Waiting patiently for the lightweight title shot

    With his performance against Donald Cerrone on Saturday night, Anthony Pettis made a believer out of many fight fans. One of those who now thinks Pettis belongs in the title shot conversation is UFC president Dana White.

    While the next bout for UFC lightweight champion Benson Henderson is set with Strikeforce champion Gilbert Melendez in April, Pettis has set himself up as the obvious next man up.

    "I think the Melendez fight is pretty set, but (Pettis is) next. I can't say enough things about the kid tonight. That was incredible," White said in the postfight press conference.

    The last time Pettis had a title shot, he had a wrench thrown into the plans. Pettis won the WEC lightweight belt in the promotion's final fight. A title shot was promised to whoever had the belt when the WEC merged with the UFC.

    But two weeks after Pettis won the belt, Frankie Edgar and Gray Maynard faced off for the belt. They fought to a draw and Edgar kept the belt, but Maynard was given an immediate rematch.

    Instead of waiting for the title shot then, Pettis fought Clay Guida. He lost a decision, and the title shot was gone. This time, he's not going to let the title shot slip through his hands.

    "If it's a guaranteed title shot, then I'm waiting. That was my goal this year, and I'm definitely going to wait and get better," Pettis said.

    The way title shots have been going in the UFC, there's no way to know if Pettis is making the right call. However, what Pettis is doing is setting himself up as the go-to guy if the UFC needs him. Melendez has had to postpone fights because of injuries in the past, and you never know what could happen as fighters prepare for their bouts.

    Source: http://sports.yahoo.com/blogs/mma-cagewriter/next-anthony-pettis-waiting-patiently-lightweight-title-shot-172409772--mma.html

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    Sunday, January 27, 2013

    Once GOP stronghold, West veers into Dems' column

    DENVER (AP) ? A political generation ago, the West signaled the nation's rightward swing, from the emergence of Ronald Reagan to the success of tax-limitation ballot measures in California and Colorado.

    Now, however, the fabled expanse of deserts, jagged peaks, and emerald coastlines is trending in a different direction.

    The West has become largely Democratic terrain.

    Voters in Washington state in November legalized marijuana and upheld the legality of gay marriage. New Mexico was once a tightly contested state, but Republicans ceded it to Democrats in the presidential campaign.

    There are, as always, exceptions.

    Lightly populated Idaho and Wyoming remain strongly Republican, as does Utah. Democrats are struggling in Arizona, where the immigration debate has given Republicans a lock on statewide offices but may provide Democrats an opening by firming up their support among the state's growing Hispanic population.

    Still, the overall trend is clear, according to analysts on all sides of the political spectrum.

    "It's just a different world," said Bill Carrick, a Democratic strategist in Los Angeles who has worked widely in the region. "Nevada became the next California and now Arizona looks like it will become the next Nevada. ... It's just pushing the West further and further from Republicans."

    The shift in a region already imbued with a libertarian spirit is the result of several factors. One is the growing number of people who are seeking a better quality of life by moving from more liberal states. Also, the expanding immigrant population is turned off by increasingly hard-line Republican immigration proposals.

    "Look at the migration patterns," said Sig Rogich, a Republican consultant in Las Vegas who worked on Reagan's presidential campaigns. "You're seeing the aftermath of a new generation of young men and women whose parents moved westward."

    Western states generally have weak political parties, part of the legacy of their political maturation during the progressive era at the start of the 20th century. Most local elections are nonpartisan affairs and voters often have the right to set policy unilaterally via ballot initiative. Western voters long have cherished nonpartisan independence, even when they voted a relatively straight party ticket.

    "The West is the most American part of America," said Dave Kopel of the Independence Institute, a libertarian think tank in Denver. "It is a place where you have much more respect for individual choice and you have more ability to be who you want to be."

    During the 1980s and 1990s, that libertarian streak fed a series of Republican victories as voters approved tax-limitation initiatives, protested federal environmental rules and kept statehouses firmly in the GOP's hands. But nowadays it means something else, Carrick said.

    "The libertarian thing is no longer about property rights or gun rights," he said. "It's now about letting people live their lives as they choose."

    Ironically, Republicans' success may have contributed to that shift.

    The party managed to enshrine staunch anti-tax measures in several states' constitutions through ballot initiatives, making it very difficult to raise taxes in California, Colorado and Washington state.

    As a result, Democrats can't easily raise revenue, but they also can't be attacked for doing so, said Ron Dotzauer, a Seattle-based Democratic strategist. "They can't be defined as the pro-tax group because they can't tax," he said.

    There are prominent Republicans who demonstrate that the party can still win the region.

    Brian Sandoval in Nevada and Susana Martinez in New Mexico are popular Republican governors, but their relatively moderate stances often put them at odds with the national party. Both, for example, just agreed to the Medicaid expansion under President Barack Obama's health care plan, something that is anathema to many conservative Republicans.

    "People appreciate a leader who takes more pragmatic approaches," said Nicole McCleskey, a New Mexico-based GOP pollster who advises Martinez.

    McCleskey argued that Democrats' success in the region is overstated and she noted that, outside of California, Republicans in 2012 only lost one Western congressional seat. As an example of how Republicans can succeed, she cited New Mexico, where the party picked up seats in the Legislature despite the Obama wave.

    But McCleskey acknowledged that New Mexico Republicans were helped by the national GOP basically giving up on the presidential race in the state. GOP presidential nominee Mitt Romney did not contest the state, minimizing the damage of a divisive presidential campaign.

    "We were able to localize a lot of these races and build on the change that has taken place with a strong Republican governor," she said. "Republicans fought on state issues and the Democrats tried to fight on national issues."

    Jill Hanauer is a Democratic strategist who engineered her party's takeover of the Colorado Legislature in 2004. She agrees with McCleskey that the West cannot be considered a Democratic lock.

    "The reason Democrats or progressives are winning is that Republicans got fat and happy," said Hanauer, who is now president of Project New America, a political data and strategy company in Denver. "The worst thing that can happen for Democrats is to take it for granted."

    In 2002, Ruy Teixeira, a Washington, D.C.-based Democratic strategist, co-wrote "The Emerging Democratic Majority," which predicted that demographic and social trends would turn parts of the country that were deep red, such as the interior Mountain West, into Democratic-leaning states. The book, published shortly after Republicans took back the U.S. Senate in the 2002 elections, was received skeptically.

    Last year, Teixeira and other researchers published a new book on the Mountain West as America's new swing region. Now there was little pushback.

    Teixeira said the West's shift has been dramatic because of the heavy migration to the region. Another factor is the ballot initiative process, which magnifies political trends by making it easier to enact dramatic policy changes such as marijuana legalization.

    But he said in an interview that what's happened to the West is not very different from what's taking place across the country. Surveys for his book last year found it only slightly more libertarian on social issues and holding similar views toward government and taxation as other parts of the country. That, he said, is bad news for Republicans ? their problem is national, not regional.

    "It's not like there's something in the water in state X that's making them harder for Republicans," Teixeira said. "It's just the same series of changes that are working themselves out in all states."

    ___

    Follow Nicholas Riccardi on Twitter at www.twitter.com/nickriccardi

    Source: http://news.yahoo.com/once-gop-stronghold-west-veers-dems-column-155520480--election.html

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    North Korean leader vows strong action

    FILE - In this Sunday, April 15, 2012 file image made from KRT video, North Korean leader Kim Jong Un applauds before giving his first public speech during a massive celebration marking the 100th birthday of national founder Kim Il Sung at Kim Il Sung Square in Pyongyang, North Korea. North Korea's state news agency says leader Kim Jong Un has vowed at a meeting of top security and foreign officials to take "substantial and high-profile important state measures.", Saturday, Jan. 26, 2013. (AP Photo/KRT via AP video, FILE) NORTH KOREA OUT, TV OUT

    FILE - In this Sunday, April 15, 2012 file image made from KRT video, North Korean leader Kim Jong Un applauds before giving his first public speech during a massive celebration marking the 100th birthday of national founder Kim Il Sung at Kim Il Sung Square in Pyongyang, North Korea. North Korea's state news agency says leader Kim Jong Un has vowed at a meeting of top security and foreign officials to take "substantial and high-profile important state measures.", Saturday, Jan. 26, 2013. (AP Photo/KRT via AP video, FILE) NORTH KOREA OUT, TV OUT

    South Korean army soldiers patrol along a barbed-wire fence in Paju, South Korea, near the demilitarized zone (DMZ) of Panmunjom, Sunday, Jan. 27, 2013. North Korean leader Kim Jong Un convened top security and foreign affairs officials and ordered them to take "substantial and high-profile important state measures," state media said Sunday, indicating that he plans to push forward with a threat to explode a nuclear device in defiance of the United Nations. (AP Photo/Ahn Young-joon)

    South Korean army soldiers patrol along a barbed-wire fence at the Imjingak Pavilion in Paju, South Korea, near the demilitarized zone (DMZ) of Panmunjom, Sunday, Jan. 27, 2013. North Korean leader Kim Jong Un convened top security and foreign affairs officials and ordered them to take "substantial and high-profile important state measures," state media said Sunday, indicating that he plans to push forward with a threat to explode a nuclear device in defiance of the United Nations. (AP Photo/Ahn Young-joon)

    This Jan. 4, 2013 satellite image provided by GeoEye shows North Korea's Punggye-ri nuclear test facility. This and other recent satellite photos show North Korea could be almost ready to carry out its threat to conduct a nuclear test, a U.S. research institute said Friday, Jan. 25, 2013. The images of the Punggye-ri site where nuclear tests were conducted in 2006 and 2009 reveal that over the past month roads have been kept clear of snow and that North Koreans may be sealing the tunnel into a mountainside where a nuclear device would be detonated. But it remains difficult to discern North Korea's true intentions as a test would be conducted underground. The analysis was provided to The Associated Press by 38 North, the website of U.S.-Korea Institute at Johns Hopkins School of Advanced International Studies. (AP Photo/GeoEye Satellite Image)

    SEOUL, South Korea (AP) ? North Korean leader Kim Jong Un convened top security and foreign affairs officials and ordered them to take "substantial and high-profile important state measures," state media said Sunday, indicating that he plans to push forward with a threat to explode a nuclear device in defiance of the United Nations.

    The meeting of top officials led by Kim makes clear that he backs Pyongyang's defiant stance in protest of U.N. Security Council punishment for a December rocket launch. The dispatch in the official Korean Central News Agency did not say when the meeting took place.

    Last week, the Security Council condemned North Korea's Dec. 12 launch of a long-range rocket as a violation of a ban against nuclear and missile activity. The council, including North Korea ally China, punished Pyongyang with more sanctions and ordered the regime to refrain from a nuclear test ? or face "significant action."

    North Korea responded by rejecting the resolution and maintaining its right to launch a satellite into orbit as part of a peaceful civilian space program.

    It also warned that it would keep developing rockets and testing nuclear devices to counter what it sees as U.S. hostility. A rare statement was issued Thursday by the powerful National Defense Commission, the top governing body led by Kim.

    Kim's order for strong action and the recent series of strong statements indicate he intends to conduct a nuclear test in the near future to show "he is a young yet powerful leader both domestically and internationally," said Chin Hee-gwan, a North Korea expert at South Korea's Inje University.

    North Korea cites a U.S. military threat in the region as a key reason behind its drive to build nuclear weapons. The two countries fought on opposite sides of the Korean War, which ended after three years in 1953 with an armistice, not a peace treaty. The U.S.-led U.N. Command mans the Demilitarized Zone dividing the two Koreas, and Washington stations more than 28,000 troops in South Korea to protect its ally.

    North Korea is estimated to have enough weaponized plutonium for four to eight bombs, according to American nuclear scientist Siegfried Hecker, who visited the country's nuclear complex northwest of Pyongyang in November 2010.

    However, it is not known whether North Korean scientists have found a way to build nuclear warheads small enough to mount on a long-range missile.

    Experts say regular tests are needed to perfect the technique, and another atomic test could take the country closer to its goal of building a warhead that can be mounted on a missile designed to strike the United States. North Korea has carried out two nuclear tests, in 2006 and 2009.

    South Korean defense officials say North Korea is technically ready to conduct a nuclear test in a matter of days.

    Satellite photos taken Wednesday show that over the past month, roads have been kept clear of snow and that North Koreans may have been sealing the tunnel into a mountainside where a nuclear device would be detonated.

    Analysis of the images of the Punggye-ri site was provided Friday to The Associated Press by 38 North, the website of the U.S.-Korea Institute at Johns Hopkins School of Advanced International Studies.

    Kim could order a nuclear test ahead of the Feb. 16th birthday of his late father and former leader Kim Jong Il to "create a festive mood," Chin predicted. Kim Jong Il died at age 69 in December 2011.

    The U.S., South Korea and other countries have warned North Korea not to go ahead with a nuclear test, saying that would only deepen the country's international isolation.

    After meeting with Chinese officials Friday, U.S. envoy for North Korea Glyn Davies said a nuclear test would set back efforts to restart regional talks on the North's nuclear disarmament.

    North Korea has accused the U.S. and South Korea of leading the push for the U.N. Security Council resolution.

    Sunday's KCNA dispatch said the U.N. punishment indicates U.S. hostility toward North Korea has reached its highest point. North Korea also warned South Korea on Friday of "strong physical countermeasures" if Seoul takes part in the U.N. sanctions.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-27-NKorea-Nuclear/id-297685c11b0a4e07a862f98cbd57f548

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    Saturday, January 26, 2013

    Ravens' Caldwell still longs to be head coach

    Baltimore Ravens offensive coordinator Jim Caldwell, back left, looks on as quarterback Joe Flacco warms up during NFL football practice at the team's training facility in Owings Mills, Md., Friday, Jan. 25, 2013. The Ravens are scheduled to face the San Francisco 49ers in Super Bowl XLVII in New Orleans on Sunday, Feb. 3. (AP Photo/Patrick Semansky)

    Baltimore Ravens offensive coordinator Jim Caldwell, back left, looks on as quarterback Joe Flacco warms up during NFL football practice at the team's training facility in Owings Mills, Md., Friday, Jan. 25, 2013. The Ravens are scheduled to face the San Francisco 49ers in Super Bowl XLVII in New Orleans on Sunday, Feb. 3. (AP Photo/Patrick Semansky)

    Baltimore Ravens offensive coordinator Jim Caldwell listens at a news conference at the team's training facility in Owings Mills, Md., Friday, Jan. 25, 2013. The Ravens are scheduled to face the San Francisco 49ers in NFL football's Super Bowl XLVII in New Orleans on Sunday, Feb. 3. (AP Photo/Patrick Semansky)

    Baltimore Ravens offensive coordinator Jim Caldwell speaks at a news conference at the team's training facility in Owings Mills, Md., Friday, Jan. 25, 2013. The Ravens are scheduled to face the San Francisco 49ers in NFL football's Super Bowl XLVII in New Orleans on Sunday, Feb. 3. (AP Photo/Patrick Semansky)

    Baltimore Ravens running back Ray Rice, left, stands with offensive coordinator Jim Caldwell during NFL football practice at the team's training facility in Owings Mills, Md., Friday, Jan. 25, 2013. The Ravens are scheduled to face the San Francisco 49ers in Super Bowl XLVII in New Orleans on Sunday, Feb. 3. (AP Photo/Patrick Semansky)

    OWINGS MILLS, Md. (AP) ? Jim Caldwell enjoys his job as offensive coordinator of the Baltimore Ravens, and he's quite good at it.

    Before taking over in early December Caldwell had never held the position at any level ? yet the Ravens' attack has flourished under his direction. Quarterback Joe Flacco has looked sharp, the play-calling has been unpredictable and Baltimore has scored 90 points in three playoff games to earn a berth in the Super Bowl.

    Caldwell's success prompted head coach John Harbaugh to ask him to retain the post in 2013. Caldwell appreciates the opportunity, but has no intention of making "Offensive Coordinator, Baltimore Ravens" the last line on his resume.

    The 58-year-old Caldwell wants to be a head coach. He did it in Indianapolis from 2009-11, and is itching for another crack at the top job in his profession.

    "At some point in time, if the Lord wills it, I'd love to be able to do it again," Caldwell said Friday. "But it may not happen. Everybody in our profession is looking for an opportunity to run their own program, and I'm no different than anybody else in that regard."

    Caldwell might have gotten the chance to at least interview for an opening if he wasn't so busy helping the Ravens earn a date with San Francisco in the Super Bowl next Sunday.

    "I had a couple of GMs tell me, 'If it weren't for your guys' success in the playoffs and continuing to play, then he would have been someone we would have interviewed," Ravens general manager Ozzie Newsome said. "Hopefully next year we're in the same spot, and it will be tough for him to get interviews again. Really, though, I can see him getting that opportunity a year from now."

    Caldwell certainly is a viable candidate for a head coaching job. He took the Colts to the Super Bowl in 2009 and was instrumental in the development of quarterback Peyton Manning. He's also provided the Baltimore offense with a boost after replacing the fired Cam Cameron on Dec. 10.

    Some coaches are fiery. Some break clipboards to get a player's attention. Caldwell does none of that.

    "Man, he is so humble, laid back," Baltimore receiver Jacoby Jones said. "But he's a smart man. He reads a lot of books, gives you a lot of quotes. He's so diverse."

    The NFL's Rooney Rule was designed to provide diversity among NFL head coaches and GMs, but if Caldwell ? an African American with impressive credentials ? can't get an interview, then maybe it's time to fix the process.

    "I do think that it's something that certainly needs to be revisited, and is going to be revisited," Caldwell said. "I'm not one of the individuals that started that particular drive to do so. There's been a lot of very intelligent men that have looked at this thing and talked about it in depth, so I think that's going to happen.

    In the meantime, Caldwell is preparing for the Super Bowl while dozens of other coaches are at home looking forward to next year. So, despite not getting an interview, he has no regrets.

    "None whatsoever. I'd certainly rather be right where I am right now, with you asking me this question," he said. "It just doesn't happen that often in your career to be fortunate enough to have this opportunity. I'm thankful. The other things, they'll take care of themselves somewhere down the road."

    Caldwell deserves plenty of credit for Baltimore's surprising run to the Super Bowl. In the six games since he's taken over, the Ravens have averaged 26.2 points and 406.2 yards of offense. During the playoffs, Baltimore has scored touchdowns on eight of 10 trips inside the opponent's 20-yard line.

    "What coach Caldwell has done has kept the offense simple and basic," running back Ray Rice said. "He put the game into Joe Flacco's hands, and Joe has done a great job ? phenomenal job ? of leading us to where we needed to be. We are right here where we want to be right now."

    And maybe, so is Caldwell. For now, anyway. He expressed genuine appreciation and thanks Friday when talking about being asked to return in 2013.

    "I'm excited about it. Certainly very honored and humbled as well," he said. "It's a great opportunity for me, in particular working within this organization. I'm looking forward to it, but right now I'm looking forward to this next ball game we've got coming up. That's the most important thing."

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-01-25-FBN-Ravens-Caldwell/id-c2166a7da598435297c2c514c8793599

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    Nonprofit task force to be chaired by economic development leader ...


    By Tribune-Review

    Published: Friday, January 25, 2013, 3:50?p.m.
    Updated 6 hours ago

    The city task force charged with squeezing more money from nonprofits is in place.

    City officials on Friday announced that the task force, which the Intergovernmental Cooperation Authority asked the city to create as a condition of passing the 2013 budget, has 36 members from the business, nonprofit, foundation, academic, labor, civic and governmental sectors.

    Don Smith, president of the Regional Industrial Development Corp. in O?Hara, will serve as the task force?s chair.

    The task force has a June 30 deadline to submit a report to the city and ICA, one of the city?s two state-appointed financial overseers. Meetings will be open to the public. Dates and locations will be announced in the coming weeks, the mayor?s office said.

    Critics contend that the city?s largest tax-exempt nonprofits should pay more for the services they consume, beyond the charity they provide.

    A full list of the task force?s members can be found at apps.pittsburghpa.gov/mayor/TaskForceMembers.pdf.

    You must be signed in to add comments

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    Source: http://triblive.com/news/adminpage/3364563-74/force-task-announced

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    Immune cell suicide alarm helps destroy escaping bacteria

    Friday, January 25, 2013

    Cells in the immune system called macrophages normally engulf and kill intruding bacteria, holding them inside a membrane-bound bag called a vacuole, where they kill and digest them.

    Some bacteria thwart this effort by ripping the bag open and then escaping into the macrophage's nutrient-rich cytosol compartment, where they divide and could eventually go on to invade other cells.

    But research from the University of North Carolina School of Medicine shows that macrophages have a suicide alarm system, a signaling pathway to detect this escape into the cytosol. The pathway activates an enzyme, called caspase-11, that triggers a program in the macrophage to destroy itself.

    "It's almost like a thief sneaking into the house not knowing an alarm will go off to knock down the walls and expose him to capture by the police," says study senior and corresponding author Edward Miao, PhD, assistant professor of microbiology and immunology at UNC. "In the macrophage, this cell death, called pyroptosis, expels the bacterium from the cell, exposing it to other immune defense mechanisms."

    A report of the research appears online in the journal Science on Thursday January 24, 2013.

    Miao, also a member of the UNC Lineberger Comprehensive Cancer Center, says the new findings show that having this detection pathway protects mice from lethal infection with the type of vacuole-escaping Burkholderia species: B. thailandensis and B. pseudomallei.

    Both are close relatives. But they differ in lethality. B. pseudomallei is potentially a biological weapon. Used in a spray, it could potentially infect people via aerosol route, causing sickness and death. Moreover, it also could fall into a latent phase, "essentially turning into a 'sleeper' inside the lungs and hiding there for decades," Miao explains. In contrast, B. thailandensis, which shares many properties with its species counterpart, is not normally able to cause any disease or infection

    These environmental bacteria are ubiquitous throughout S.E. Asia, and were it not for the caspase-11 pathway defense system, that part of the world could be uninhabitable, Miao points out.

    This grim possibility clearly emerged in the study. Mice that lack the caspase-11 detection pathway succumb to infection not only by B. pseudomallei, but also to the normally benign B. thailandensis. "Thus caspase-11 is critical for surviving exposure to ubiquitous environmental pathogens," the authors conclude.

    Miao points to research elsewhere showing that the pathway's abnormal activation in people with septic shock, overwhelming bacterial infection of the blood, is associated with death. "We discovered what the pathway is supposed to do, which may help find ways to tone it down in people with that critical condition.

    As to bioterrorism, the researcher says it may be possible to use certain drugs already on the market that safely induce the caspase-11 pathway. "Since this pathway requires pre-stimulation with interferon cytokines, it is conceivable that pre-treating people with interferon drugs could ameliorate a bioterror incident. This could be quite important in the case of Burkholderia, since these bacteria are naturally resistant to numerous antibiotics.

    "But first we have to find out if they would work in animal models, and consider the logistics of interferon stockpiling, which are currently cost prohibitive."

    ###

    University of North Carolina Health Care: http://www.med.unc.edu

    Thanks to University of North Carolina Health Care for this article.

    This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

    This press release has been viewed 57 time(s).

    Source: http://www.labspaces.net/126466/Immune_cell_suicide_alarm_helps_destroy_escaping_bacteria

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    Friday, January 25, 2013

    Nottingham expertise in major European drug discovery partnership

    Nottingham expertise in major European drug discovery partnership [ Back to EurekAlert! ] Public release date: 24-Jan-2013
    [ | E-mail | Share Share ]

    Contact: Emma Thorne
    emma.thorne@nottingham.ac.uk
    44-011-595-15793
    University of Nottingham

    Scientists from Nottingham are part of a major European-wide project aimed at developing the next generation of medicines that are more effective and longer lasting.

    The academics from The University of Nottingham are using high-tech laser technology to study in real-time how drug molecules 'stick' to receptors or proteins on the surface of cells in our body in an effort to learn more about how drugs work.

    Learning how drugs interact with the cells in our body could lead to further clues on how to design drugs for chronic and life threatening illnesses, such as cancer and asthma, which are better at treating patients and don't have to be taken as regularly as current therapies.

    Professor Steve Hill, in the University's School of Biomedical Sciences, is leading the Nottingham side of the project. He said: "The ultimate aim here is to find new ways of interacting with some of those receptors which might form better drugs.

    "Nottingham's expertise is in using clever ways to visualise in real-time the speed at which drugs bind and unbind to proteins in the body and to learn about how adding other drugs at the same time may improve or inhibit that.

    "The goal will be to develop new medicines that patients don't have to remember to take twice or three times a day or with a meal just one dose a day would be enough."

    Bench to bedside

    Nottingham is part of a new 18m consortium supported by Europe's Innovative Medicines Initiative (IMI) and major pharmaceutical companies aimed at tackling the development of new drugs. During the course of the five-year project around 500,000 of that funding will come to Nottingham.

    Almost 90 per cent of experimental drugs that are tested through expensive clinical trials fail at the final hurdle because they don't work as well as they should. In fact, only one in around 15,000 potential new drugs will make it to market a process that can take almost 15 years from bench to bedside.

    The new consortium, led by the German pharma company Bayer HealthCare and Leiden University in the Netherlands and involving a number of universities and SMEs, is entitled Kinetics for Drug Discovery (K4DD) and centres around the recent discovery that the length of time that a drug molecule is bound to proteins in the body may have a direct impact on the effectiveness of the medicine.

    The Nottingham team, which also involves Dr Steve Briddon in Biomedical Sciences and Dr Barrie Kellam in the School of Pharmacy, will be bringing their expertise of fluorescent ligand technology to the project.

    Investigating effectiveness

    Their work centres on G protein-coupled receptors a group of around 400-500 proteins which are the most targeted group of proteins for current medicines. Around 30 per cent of current medicines target the group but currently only successfully use around 40 of the available proteins.

    The Nottingham work will centre on new technologies to gain an insight into how the remainder of these targets could be exploited.

    They will be using technology invented in Nottingham and the basis for the University spin-out company CellAura Technologies Ltd based in BioCity in which they label a drug molecule with a fluorescent chemical and then detect the light it gives off when interacting with receptors in the cell membrane using high-tech laser confocal microscopes and single molecule detection techniques (fluorescence correlation spectroscopy).

    In this way they can observe the way in which drugs are binding and unbinding as it is happening which gives an accurate indication of how effective a drug is and how long its effects are likely to last.

    As part of the consortium, Nottingham will be leading the way on the educational side devising training in research, business and communications skills for postdoctoral students from all over Europe, some of which will be based here at the University during the course of the five year project.

    ###



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    Nottingham expertise in major European drug discovery partnership [ Back to EurekAlert! ] Public release date: 24-Jan-2013
    [ | E-mail | Share Share ]

    Contact: Emma Thorne
    emma.thorne@nottingham.ac.uk
    44-011-595-15793
    University of Nottingham

    Scientists from Nottingham are part of a major European-wide project aimed at developing the next generation of medicines that are more effective and longer lasting.

    The academics from The University of Nottingham are using high-tech laser technology to study in real-time how drug molecules 'stick' to receptors or proteins on the surface of cells in our body in an effort to learn more about how drugs work.

    Learning how drugs interact with the cells in our body could lead to further clues on how to design drugs for chronic and life threatening illnesses, such as cancer and asthma, which are better at treating patients and don't have to be taken as regularly as current therapies.

    Professor Steve Hill, in the University's School of Biomedical Sciences, is leading the Nottingham side of the project. He said: "The ultimate aim here is to find new ways of interacting with some of those receptors which might form better drugs.

    "Nottingham's expertise is in using clever ways to visualise in real-time the speed at which drugs bind and unbind to proteins in the body and to learn about how adding other drugs at the same time may improve or inhibit that.

    "The goal will be to develop new medicines that patients don't have to remember to take twice or three times a day or with a meal just one dose a day would be enough."

    Bench to bedside

    Nottingham is part of a new 18m consortium supported by Europe's Innovative Medicines Initiative (IMI) and major pharmaceutical companies aimed at tackling the development of new drugs. During the course of the five-year project around 500,000 of that funding will come to Nottingham.

    Almost 90 per cent of experimental drugs that are tested through expensive clinical trials fail at the final hurdle because they don't work as well as they should. In fact, only one in around 15,000 potential new drugs will make it to market a process that can take almost 15 years from bench to bedside.

    The new consortium, led by the German pharma company Bayer HealthCare and Leiden University in the Netherlands and involving a number of universities and SMEs, is entitled Kinetics for Drug Discovery (K4DD) and centres around the recent discovery that the length of time that a drug molecule is bound to proteins in the body may have a direct impact on the effectiveness of the medicine.

    The Nottingham team, which also involves Dr Steve Briddon in Biomedical Sciences and Dr Barrie Kellam in the School of Pharmacy, will be bringing their expertise of fluorescent ligand technology to the project.

    Investigating effectiveness

    Their work centres on G protein-coupled receptors a group of around 400-500 proteins which are the most targeted group of proteins for current medicines. Around 30 per cent of current medicines target the group but currently only successfully use around 40 of the available proteins.

    The Nottingham work will centre on new technologies to gain an insight into how the remainder of these targets could be exploited.

    They will be using technology invented in Nottingham and the basis for the University spin-out company CellAura Technologies Ltd based in BioCity in which they label a drug molecule with a fluorescent chemical and then detect the light it gives off when interacting with receptors in the cell membrane using high-tech laser confocal microscopes and single molecule detection techniques (fluorescence correlation spectroscopy).

    In this way they can observe the way in which drugs are binding and unbinding as it is happening which gives an accurate indication of how effective a drug is and how long its effects are likely to last.

    As part of the consortium, Nottingham will be leading the way on the educational side devising training in research, business and communications skills for postdoctoral students from all over Europe, some of which will be based here at the University during the course of the five year project.

    ###



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


    Source: http://www.eurekalert.org/pub_releases/2013-01/uon-nei012413.php

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    Video: Next Week's Earnings Preview

    Sorry, Readability was unable to parse this page for content.

    Source: http://video.msnbc.msn.com/cnbc/50590441/

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    5 Simple Small Business Marketing Tips - FamousWSIResults, New ...

    Last updated 7 hours 30 minutes ago

    Interested In Some Affordable Small Business Marketing? Tips?

    If you are a small business on a limited marketing budget, there are ways to get your product or service noticed that cost little to no money.

    Make 2013 the year you step up your efforts to engage your customers. Marketing trends are changing rapidly and customers expect business to keep up.

    Simple strategies, such as interacting with customers via facebook, twitter or online directories cost nothing, yet can help your business gain a following of loyal customers.

    Think outside the box and deliver fresh content that will get your business noticed. Have a little fun with social media and engage with your customers so that they'll continue to like your business!

    Check Out These 5 Simple Small Business Marketing Tips Below that cost little to no money.

    Need a little Help?

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    Source: http://famouswsiresults.wsicast.com/633145/2013/01/25/5-simple-small-business-marketing-tips.html

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    Thursday, January 24, 2013

    Oops! Twitter's new video-sharing service lacks privacy settings

    2 hrs.

    Twitter's new video-sharing service Vine?feels a lot like Instagram for videos. It's neat, easy to use, and can produce fun clips. Just?one problem: There are no privacy settings whatsoever.

    Right now, you can create and share Vine?videos using an iOS app?only. All you have to do is point your iPhone (or iPod Touch) at something and press your finger to the screen to record a clip up to six seconds in length (both sound and motion are captured, of course). Once satisfied with your final product, you can share it to Vine, Twitter and Facebook.?

    Unfortunately as soon as you post?the clip to Vine, you've lost any control over who views it or interacts with it. There's no way to create a private Vine account nor can you choose who may follow you or view your profile on the video-sharing service. And while you can delete comments from your Vine posts, there's no way to block or report abusive users. (Though you can report videos as inappropriate.)

    NBC News asked Twitter about the lack of privacy settings on Vine, and we were?pointed to the service's Help site, which confirms what we've experienced. ?"Profiles and videos on Vine are public, and anyone on the service can view them," a note declares before clarifying that?you can certainly?use Vine to create a video and save it to your Camera Roll rather than sharing it.?But this?isn't enough to?satisfy our need for actual privacy controls. We're instead left with the promise that the team?behind the service will "add more ways for you to control the visibility of your content in a future version of Vine."?

    Want more tech news?or interesting?links? You'll get plenty of both if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts,?or circling her?on?Google+.

    Source: http://www.nbcnews.com/technology/technolog/oops-twitters-new-video-sharing-service-lacks-privacy-settings-1B8101730

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    White House says Obama supports women in combat (The Arizona Republic)

    Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

    Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/279258175?client_source=feed&format=rss

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